Composition analysis
A chemical compound which adds odours to dental products
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It is thought that calcium glycerophosphate may act through a variety of mechanisms to produce an anti-caries effect , These include increasing acid-resistance of the enamel, increasing enamel mineralization, modifying plaque, acting as a pH-buffer in plaque, and elevating Calcium and phosphate levels.
When used as an electrolyte replacement, calcium glycerophosphate donates Calcium and inorganic phosphate. Calcium glycerophosphate is preferable to calcium phosphate due to its increased solubility. Compared to combination calcium gluconate and potassium phosphate, calcium glycerophosphate produces greater phosphate retention which allows for increased Calcium retention and ultimately greater incorporation of the ions into bone structure
By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings, and fillings. It is also present in dental or oral hygiene products due to its cariostatic effects.
Some adverse effects of carbamide peroxide as a dental bleaching agent include dentin sensitivity and/or gingival irritation led by unstable and reactive H+ free radicals and low pH from prolonged use. It may also alter enamel surface morphology via enamel mineral loss and surface roughening. The FDA considers carbamide peroxide to be safe in oral mucosal injury drug products as an oral wound healing agent, although there is insufficient data to establish general recognition of the effectiveness of this ingredient as an oral wound healing agent. It is available in OTC otic drugs as non-
water, non-oil-based solutions used to soften, loosen and remove excessive ear wax, or cerumen.
Glycerol (also called glycerine or glycerin) is a simple polyol compound.
Glycerin is mildly antimicrobial and antiviral and is an FDA approved treatment for wounds. The Red Cross reports that an 85% solution of glycerin shows bactericidal and antiviral effects, and wounds treated with glycerin show reduced inflammation after roughly 2 hours. Due to this it is used widely in wound care products, including glycerin based hydrogel sheets for burns and other wound care. It is approved for all types of wound care except third degree burns, and is used to package donor skin used in skin grafts. There is no topical treatment approved for third degree burns, and so this limitation is not exclusive to glycerin.
Glycerol is used in medical, pharmaceutical and personal care preparations, often as a means of improving smoothness, providing lubrication, and as a humectant.
In toothpastes Glycerol holds onto water and prevents the toothpaste from drying out in the tube, and also prevents dryness in the mouth during brushing.
It can help reduce bacterial activity by reducing the available water activity and therefore has a protective action against tooth decay. Glycerin does not damage gums or tooth enamel.
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Glycerin as ingredient of foods,cosmetic products ,toothpaste and ...may cause : Upset stomach, Stomach cramps, Gas, Diarrhea, Burning, Rectal irritation.
Glycerin does not damage gums or tooth enamel.
A very serious allergic reaction to this product is rare. However, seek immediate medical attention if you notice any of the following symptoms of a serious allergic reaction:Redness, stinging, or irritation, rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.Redness, stinging, or irritation at the application site may occur.
As with all other New Directions Aromatics products, PEG 40 Hydrogenated Castor Oil Raw Material is for external use only. It is imperative to consult a medical practitioner before using this product for therapeutic purposes. Pregnant and nursing women as well as those with sensitive, irritated, broken, injured, or damaged skin are especially advised not to use PEG 40 Hydrogenated Castor Oil Raw Material without the medical advice of a physician. This product should always be stored in an area that is inaccessible to children, especially those under the age of 7.
Prior to using PEG 40 Hydrogenated Castor Oil Raw Material, a skin test is recommended. This can be done by dissolving 1 tsp PEG 40 Hydrogenated Castor Oil Raw Material in 1 tsp of a preferred Carrier Oil and applying a dime-size amount of this blend to a small area of skin that is not sensitive. PEG 40 Hydrogenated Castor Oil must never be used near the inner nose and ears or on any other particularly sensitive areas of skin. Potential side effects of PEG 40 Hydrogenated Castor Oil include the itching, blistering, burning, and scaling of skin as well as hives. In the event of an allergic reaction, discontinue use of the product and see a doctor, pharmacist, or allergist immediately for a health assessment and appropriate remedial action. To prevent side effects, consult with a medical professional prior to use.
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Common side effects:
A Feeling Of General Discomfort Called Malaise
A Sleep Disorder
Dehydration
Excessive Thirst
Intense Abdominal Pain
Irritation Of The Rectum
Nausea
Stomach Cramps
Swelling Of The Abdomen
Upper Abdominal Pain
Vomiting
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Propylene glycol is “generally recognized as safe” (GRAS) by the US Food and Drug Administration (FDA).
In the US, it can be used as a direct and indirect food additive. In Europe, it is only allowed to be used in food as a solvent for colors, emulsifiers, antioxidants and enzymes, with up to 0.45 grams per pound (1 gram/kg) allowed in the final food product.
The World Health Organization recommends a maximum intake of 11.4 mg of propylene glycol per pound of body weight (25 mg/kg) per day. The estimated exposure to propylene glycol through foods in the US is 15 mg per pound (34 mg/kg) per day.
In comparison, one person who developed symptoms of toxicity was receiving 213 grams of propylene glycol per day. For a 120-pound (60-kg) adult, that is over 100 times what is found in the average diet .
There is only one documented case of toxicity caused by food.
A man drank very large amounts of cinnamon whiskey containing propylene glycol and was found unconscious. While his symptoms were also due to the alcohol, some could be attributed to the propylene glycol.
Overall, apart from people with allergies and one case of excessive consumption, there have been no other reported cases of negative or toxic effects of propylene glycol in foods.
However, as current intakes are estimated to be above the recommended level, it may be wise to reduce dietary sources where you can, especially as the primary sources are highly processed foods.
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The following is a list of possible side-effects that may occur in medicines that contain Tris. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
Irritation
Inflammation
Infection at the injection site
Tris may also cause side-effects not listed here.