R.o.c.s. Blooming Sakura

Danger 8
Danger: 8

Safe.
Good choice

Analyze ingredients for more information

INDICATIONS FOR USE
Intended for regular everyday use by adults and children over the age of 4. Ensures a high level of complex protection for the teeth and gums thanks to the effect of BIO components of natural origin, the activeness of which is preserved thanks to a special low-temperature brewing technology of the toothpaste. The MINERALIN® complex, which contains the natural enzyme bromelain, xylitol and mineral compounds – the source of calcium, phosphorus and magnesium ions, is strengthened by cherry blossom extract, which is a source of polyphenols – powerful natural antioxidants, which ensure that the extract has pronounced antimicrobial and anti-inflammatory properties. The extract used in the toothpaste is manufactured in France by the Alban Muller Int. company using a unique eco-technology that preserves all properties and characteristics of the natural product.

The MINERALIN® complex, together with the cherry blossom extract,
ensures the following pronounced effects when used:

• Brightens and shines the enamel *
• Strengthens hard dental tissues and prevents the development of caries*
• Long-lasting cleaning of the teeth and gums*
• Prevents the formation of dark plaque and calculus
• Alleviates bleeding and inflammation of the gums (symptoms of inflammation and bleeding of the gums decrease by 86% after 1 week of use)*
• Freshens the breath*
• Normalizes the makeup of the oral cavity microflora and alleviates dysbiosis (has prebiotic qualities)*
Does not contain fluoride, antiseptics. Low abrasivity.

*Confirmed during laboratory and clinical trials

ACTIVE INGREDIENTS
Treatment-and-prophylactic R.O.C.S. toothpaste for adults containing the MINERALIN® complex, which is a patented combination of ingredients: the natural proteolytic enzyme bromelain, xylitol, calcium glycerophosphate and magnesium chloride.

The toothpaste also contains cherry blossom extract, which is a source of polyphenols – powerful natural antioxidants

MECHANISM OF ACTION
BROMELAIN – a purified enzyme from pineapple fruit and stalks – gently dissolves dental plaque; prevents the attachment of bacteria to the teeth and oral mucosa; possesses anti-inflammatory properties. Has been used with success in various fields of medicine for over 30 years, including as part of pharmaceutical products, and has a high clinical effectiveness.

XYLITOL – (found in grains) protects against cariogenic bacteria in high concentrations, has prebiotic qualities; promotes the absorption of calcium

CALCIUM GLYCEROPHOSPHATE AND MAGNESIUM CHLORIDE – minerals that are known and beneficial to the human body – strengthen the enamel and dentin, restore the teeth’s whiteness*

The toothpaste includes CHERRY BLOSSOM EXTRACT, which is a source of polyphenols – powerful natural antioxidants, thanks to which the extract possesses pronounced antimicrobial and anti-inflammatory properties.

Ingredients:

Composition analysis


The main carrier for all ingredients.
Helps dissolve other soluble ingredients. Helps the mechanical process of cleaning teeth in mouthwashes.

Bromelain is a group of enzymes found in the fruit and stem of the pineapple plant.
Bromelain is a group of enzymes found in the fruit and stem of the pineapple plant. Pineapple is native to the Americas but is now grown throughout the world in tropical and subtropical regions. Historically, natives of Central and South America used pineapple for a variety of ailments, such as digestive disorders. Bromelain is promoted as a dietary supplement for reducing pain and swelling, especially of the nose and sinuses, gums, and other body parts after surgery or injury. It is also promoted for osteoarthritis, cancer, digestive problems, and muscle soreness. Topical bromelain is promoted for burns.
Danger:
Few side effects of bromelain have been reported in studies. The most commonly reported side effects have been stomach upset and diarrhea. Allergic reactions may occur in individuals who are sensitive or allergic to pineapples or who have other allergies. Little is known about whether it’s safe to use bromelain during pregnancy or while breastfeeding. Bromelain may interact with some medicines, such as the antibiotic amoxicillin. If you take medicines, talk to your health care provider before taking bromelain.

Calcium glycerophosphate is a Calcium salt of glycerophosphoric acid
It is thought that calcium glycerophosphate may act through a variety of mechanisms to produce an anti-caries effect , These include increasing acid-resistance of the enamel, increasing enamel mineralization, modifying plaque, acting as a pH-buffer in plaque, and elevating Calcium and phosphate levels. When used as an electrolyte replacement, calcium glycerophosphate donates Calcium and inorganic phosphate. Calcium glycerophosphate is preferable to calcium phosphate due to its increased solubility. Compared to combination calcium gluconate and potassium phosphate, calcium glycerophosphate produces greater phosphate retention which allows for increased Calcium retention and ultimately greater incorporation of the ions into bone structure
Danger:
By FDA, calcium glycerophosphate is considered a generally recognized as safe (GRAS) food ingredient as a nutrient supplement (source of calcium or phosphorus), or in food products such as gelatins, puddings, and fillings. It is also present in dental or oral hygiene products due to its cariostatic effects.

Danger:
Eugenolis listed by the FDA as GRAS when consumed orally, in unburned form. It is nontoxic in food but toxic upon inhalation. High doses of may cause damage to the liver (Thompson et al., 1998).


Helps prevent products from drying out, acts as a thickener and provides sweetness.
Glycerol (also called glycerine or glycerin) is a simple polyol compound. Glycerin is mildly antimicrobial and antiviral and is an FDA approved treatment for wounds. The Red Cross reports that an 85% solution of glycerin shows bactericidal and antiviral effects, and wounds treated with glycerin show reduced inflammation after roughly 2 hours. Due to this it is used widely in wound care products, including glycerin based hydrogel sheets for burns and other wound care. It is approved for all types of wound care except third degree burns, and is used to package donor skin used in skin grafts. There is no topical treatment approved for third degree burns, and so this limitation is not exclusive to glycerin. Glycerol is used in medical, pharmaceutical and personal care preparations, often as a means of improving smoothness, providing lubrication, and as a humectant. In toothpastes Glycerol holds onto water and prevents the toothpaste from drying out in the tube, and also prevents dryness in the mouth during brushing. It can help reduce bacterial activity by reducing the available water activity and therefore has a protective action against tooth decay. Glycerin does not damage gums or tooth enamel.
Danger:
Glycerin as ingredient of foods,cosmetic products ,toothpaste and ...may cause : Upset stomach, Stomach cramps, Gas, Diarrhea, Burning, Rectal irritation. Glycerin does not damage gums or tooth enamel.

Danger:
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Danger:
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Stomach upset and diarrhea may occur. Taking this product with a meal helps to reduce these effects. A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Danger:
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Skin Cancer: Applying personal care product containing parabens—especially methylparaben—can lead to UV-induced damage of skin cells and disruption of cell proliferation (cell growth rate). Daily application, in particular, can lead to increased concentrations of methylparaben because it is not completely metabolized.

Danger:
Generally, parabens don't irritate the skin or cause allergy. Other research indicates that parabens are safe as used in cosmetics and preferred since they are gentle, non-sensitizing, and highly effective. A number of commonly used parabens have had the U.S. Food and Drug Administration’s (FDA) Generally Recognized as Safe (GRAS) classification since the early 1970s. The GRAS designation means the substance is generally recognized, among qualified experts, as having been adequately shown to be safe under the conditions of its intended use. Other examples of compounds that are considered GRAS include vitamin A, wheat starch and sugar. FDA also participates on the Cosmetic Ingredient Review (CIR), an independent panel of medical and scientific experts that meets quarterly to assess the safety of cosmetic ingredients based on data in the published literature, as well as data voluntarily provided by the cosmetics industry. FDA takes the results of CIR reviews into consideration when conducting a safety assessment. In 1984, CIR reviewed the safety of parabens used in cosmetics and concluded that they were safe, even in extremely large doses. Typically parabens are used at levels ranging from 0.01 to 0.3 percent, and the CIR concluded they were safe for use in cosmetics at levels up to 25 percent. In 2012, the CIR reopened its safety report on parabens to consider all new data. As it did in 1984, the expert panel reaffirmed the safety of cosmetic products in which parabens preservatives are used.

Danger:
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The takeaway. Silicon dioxide exists naturally within the earth and our bodies. There isn't yet evidence to suggest it's dangerous to ingest as a food additive, but more research is needed on what role it plays in the body. Chronic inhalation of silica dust can lead to lung disease.

Danger:
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The Food and Drug Administration (FDA) regards SLS as safe as a food additive. Regarding its use in cosmetics and body products, the safety assessment study of SLS, published in 1983 in the International Journal of Toxicology (the most recent assessment), found that it’s not harmful if used briefly and rinsed from the skin, as with shampoos and soaps. The report says that products that stay on the skin longer shouldn’t exceed 1 percent concentration of SLS. However, the same assessment did suggest some possible, albeit minimal, risk to humans using SLS. For example, some tests found that continuous skin exposure to SLS could cause mild to moderate irritation in animals. Nevertheless, the assessment concluded that SLS is safe in formulations used in cosmetics and personal care products. Because many of these products are designed to be rinsed off after short applications, the risks are minimal. According to most research, SLS is an irritant but not a carcinogen. Studies have shown no link between the use of SLS and increased cancer risk. According to a 2015 study, SLS is safe for use in household cleaning products.

Danger:
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In the 1970s, studies performed on laboratory rats found an association between consumption of high doses of saccharin and the development of bladder cancer. However, further study determined that this effect was due to a mechanism that is not relevant to humans.Epidemiological studies have shown no evidence that saccharin is associated with bladder cancer in humans.The International Agency for Research on Cancer (IARC) originally classified saccharin in Group 2B ("possibly carcinogenic to humans") based on the rat studies, but downgraded it to Group 3 ("not classifiable as to the carcinogenicity to humans") upon review of the subsequent research. Saccharin has no food energy and no nutritional value. It is safe to consume for individuals with diabetes. People with sulfonamide allergies can experience allergic reactions to saccharin, as it is a sulfonamide derivative and can cross-react. Saccharin in toothpaste can cause burning sensations, swelling, and rashes of the mouth and lips in sensitive individuals.

Danger:
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Ingesting large amounts of sorbitol can lead to abdominal pain, flatulence, and mild to severe diarrhea. Habitual sorbitol consumption of over 20 grams (0.7 oz) per day as sugar-free gum has led to severe diarrhea, causing unintended weight loss or even requiring hospitalization. In early studies, a dose of 25g of sorbitol, eaten through the day, produced a laxative effect in only 5% of individuals. As a result of the large molecular weight of sorbitol, when large amounts of sorbitol are ingested, only a small amount of sorbitol is absorbed in the small intestine, and most of the sorbitol enters the colon, with consequent gastrointestinal effects.

Danger:
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For most people, eating foods that contain xanthan gum appears to be completely safe. While many foods contain it, it only makes up about 0.05–0.3% of a food product. Moreover, a typical person consumes less than 1 gram of xanthan gum per day. Amounts 20 times that have been proven to be safe. In fact, the Joint Expert Committee on Food Additives assigned it an acceptable daily intake of “not specified.” It gives this designation when food additives have a very low toxicity, and levels in foods are so small that they do not pose a health hazard. But people should avoid inhaling xanthan gum. Workers who handled it in powder form were found to have flu-like symptoms and nose and throat irritation. So even though you may eat many foods containing it, your intake is so small that you’re unlikely to experience either benefits or negative side effects.

Danger:
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Xylitol is generally well tolerated, but some people experience digestive side effects when they consume too much. The sugar alcohols can pull water into your intestine or get fermented by gut bacteria. This can lead to gas, bloating and diarrhea.

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